Review on the topographical effects on vascular cells for the applications in vascular conduits

Cardiovascular diseases are the leading cause of mortality worldwide and represent a pressing clinical need.  Vascular occlusions are the predominant cause of cardiovascular disease and necessitate surgical interventions such as bypass graft surgery to replace the damaged or obstructed blood vessel with a synthetic conduit.  In our review article published in Advanced Healthcare Materials, we discussed and reviewed the application of surface topography in synthetic small-diameter vascular graft and how topography affects vascular cell behaviors.

Refer to Conner A et al. The effect of biomimetic surface topography on vascular cells: implications for vascular conduits.  Advanced Healthcare Materials. 2024, 13, 2400335.