Publications

  1. Islam MS, Sproule D, Yohans J, Chenananporn F, Yim EKF, Gupta A, Mekonnen TH. Citric acid - crosslinked cellulose derivatives superabsorbent hydrogels (SAH) as sustainable alternatives for personal hygiene applications. Chemical Engineering Journal, 526: 170721. 2025. [Open Access]
  2. Ezzo N, Nguyen TH, Ren CL, Yim EKF. A Versatile Droplet Microfluidic Platform Capable of Confining Preformed Spheroids in Hydrogel Microenvironments for Downstream Growth and Analysis. ACS Biomaterials Science & Engineering, 11(10): 6248-6261. 2025. [PubMed]
  3. David D, Zaw AM, Kunihiro J, Yao Y, Yim EKF.  Substrate Topography Modulate Human Vascular Smooth Muscle Cell Proliferation and Phenotype in Proinflammatory Condition. ACS Applied Materials & Interfaces, 17(33): 46563-46582. 2025. [PubMed]
  4. Xi W, Enkhbat M, Sun F, Tone SO, Kocaba V, Peh GSL, Mehta JS, Yim EKF. Apoptotic Response of Immortalized Normal and Fuchs Endothelial Corneal Dystrophy Human Corneal Endothelial Cells to Synthetic Guttata Patterns. Investigative Ophthalmology & Visual Science, 66(8): 2933. 2025. [Open Access]
  5. Graham OF, Sun F, Yan J, Tone SO, Yim EKF. Gravitational impact on human corneal endothelial cell migration on corneal mimicking curvature. Investigative Ophthalmology & Visual Science, 66(8): 2940. 2025. [Open Access]
  6. Sun F, Xi LWQ, Luu W, Enkhbat M, Neo D, Mehta JS, Peh GSL, Yim EKF. Preclinical Models for Studying Fuchs Endothelial Corneal Dystrophy. Cells, 14(7): 505. 2025. [Open Access]
  7. Tadele DT, David D, Yim EKF, Mekonnen TH. Development and characterization of PVA-zein/α-tocopherol nonwoven mats for functional wound dressing applications. Colloids and Surfaces B: Biointerfaces, 246:114355. 2025. [Open Access]
  8. Enkhbat M, Mehta JS, Peh GSL, Yim EKF. Biomaterial-based strategies for primary human corneal endothelial cells for therapeutic applications: from cell expansion to transplantable carrier. Biomaterials Science, 13(5): 1114-1130. 2025. [Open Access]
  9. Nguyen TH, Ezzo N, Chan S, Yim EKF, Ren CL. A simple guideline for designing droplet microfluidic chips to achieve an improved single (bio)particle encapsulation rate using a stratified flow-assisted particle ordering method. Biomicrofluidics, 18(5): 054110. 2024. [PubMed]
  10. Conner A*, Yao Y*, Chan SW, Jain D, Wong SMTK, Yim EKF, and Rizwan M. High-throughput analysis of topographical cues for the expansion of murine pluripotent stem cells. Nanotechnology, 35(4): 455101, page 1-15. 2024. *co-first authors. [Open Access]
  11. Conner A*, David D*, Yim EKF. The Effects of Biomimetic Surface Topography on Vascular Cells: Implications for Vascular Conduits. Advanced Healthcare Materials,13(27): 240035. 2024. *co-first authors.  [Open Access]
  12. Yao Y*, Feng F*, Yim EKF. Fucoidan and microtopography on polyvinyl alcohol hydrogel promoted neuronal differentiation and axon guidance of pheochromocytoma 12 cells. Biomedical Materials, 18(5). 2023. *co-first authors. [Open Access]
  13. Conner A*, Mattiassi S*, Fang F, Goh E, Yim EKF. The Combined Effects of Topography and Stiffness on Neuronal Differentiation and Maturation Using a Hydrogel Platform.  Cells, 12(6): 934. 2023. *co-first authors. [Open Access]
  14. Yao Y*, Pohan G*, Cutiongco MFA, Jeong Y, Kunihiro J, Zaw AM, David D, Shangguan R, Yu ACH, Yim EKF. In vivo evaluation of compliance mismatch on intimal hyperplasia formation in small diameter vascular grafts. Biomaterials Science, 11(9): 3297-3307, 2023.  *co-first authors. [PubMed]
  15. Yao Y, Zaw AM, Anderson DEJ, Jeong Y, Kunihiro J, Hinds MT, Yim EKF. Fucoidan and topography modification improved endothelialization on acellular synthetic vascular grafts. Bioactive Materials, 22:535-550. 2022. [Open Access]
  16. Soh WWM, Zhu J, Song X, Jain D, Yim EKF, Li J.  Detachment of bovine corneal endothelial cell sheets by cooling-induced surface hydration of poly[(R)-3-hydroxybutyrate]-based thermoresponsive copolymer coating. Journal of Materials Chemistry B, 10(41):8407-8418. 2022. [Open Access]
  17. Fallon ME, Le HH, Bates NM, Yao Y, Yim EKF, Hinds MT, Anderson DEJ. Hemocompatibility of Micropatterned Biomaterial Surfaces is Dependent on Topographical Feature Size. Frontiers in Physiology, 13:983187. 2022. [Open Access]
  18. Mattiassi S*, Rizwan M*, Grisby C*, Zaw AM, Leong K, Yim EKF. Enhanced efficiency of nonviral direct neuronal reprogramming on topographical patterns. Biomaterials Science, 9:5175-5191. 2021. *^co-first authors
  19. Yao Y, Yim EKF. The development of fucoidan in cardiovascular application and the factors mediating its activities. Carbohydrate Polymers, 270:118347. 2021. [PubMed]
  20. Cui L, Yao Y, Yim EKF. The effects of surface topography modification on hydrogel properties. APL Bioengineering, 5: 031509. 2021. [Open Access]
  21. Sathe S, Jain D, Koh CG, Yim EKF. POPX2 phosphatase enhances topographical contact guidance for cell morphology and migration. Biomedical Materials,  16(2): 025020. 2021.
  22. Kukumberg M*, Zaw AM*, Wong D, Toh CM, Chan BPL, Seet RCS, Wong PTF, Yim EKF. Characterization and functional assessment of endothelial progenitor cells in ischemic stroke patients. Stem Cell Reviews and Report, 17:1-16. 2021. *co-first authors [Open Access]
  23. Jeong Y, Yao Y, Mekonnen TH, Yim EKF. Changing compliance of poly(vinyl alcohol) vascular grafts through modifying interlayer adhesion and crosslinking density. Frontier in Materials,  7:456. 2020. [Open Access]
  24. Bates NB, Heidenreich HE, Fallon ME, Yao Y, Yim EKF, Hinds MT, Anderson DEJ. Bioconjugation of a Collagen-Mimicking Peptide Onto Poly(vinyl alcohol) Encourages Endothelialization While Minimizing Thrombosis. Frontier in Bioengineering and Biotechnology, 8:1467. 2020.  [Open Access]
  25. Rizwan M, Chan S, Comeau P, Willett T, Yim EKF. Effect of sterilization treatment on mechanical properties, biodegradation, bioactivity and printability of GelMA hydrogels. Biomedical Materials, 15(6): 065017. 2020. [PMC Free Article]
  26. Tse JW, Rizwan M, Rasmussen J, Jones L, Yim EKF. Gelatin Methacrylate as an Enzyme-Controlled Release Vehicle of Hyaluronic Acid for the Treatment of Recurrent Corneal Erosion. ACS Applied Bio Materials, 3(9): 6214-6223. 2020.
  27. Jeong Y, Yao Y, Yim EKF. Current understanding of intimal hyperplasia and effect of compliance in synthetic small diameter vascular grafts. Biomaterials Science, 8(16): 4383-4395. 2020. [PMC Free Article]
  28. Zuo K, Koh LB, Charles CJ, Yim EK, Lim J, Li RR, Leo HL, Cui F, Ho P. Measurement of the Luminal Diameter of Peripheral Arterial Vasculature in Yorkshire× Landrace Swine by Using Ultrasonography and Angiography. Journal of the American Association for Laboratory Animal Science: JAALAS, 59(4): 438-444. 2020. 
  29. Pohan G, Mattiassi S, Yao Y, Zaw AM, Anderson DEJ, Cutiongco MFA, Hinds MT, Yim EKF. Effect of Ethylene Oxide Sterilization on Polyvinyl Alcohol Hydrogel Compared with Gamma Radiation. Tissue Engineering Part A, 26(19-20): 1077-1090. 2020. [PMC Free Article]
  30. Yao Y, Zaw AM, Anderson D, Hinds MT, Yim EKF. Fucoidan functionalization on poly(vinyl alcohol) hydrogels for improved endothelialization and hemocompatibility.  Biomaterials. 249, 120011. 2020 [PMC Free Article]
  31. Chan S, Rizwan M, EKF Yim. Emerging Methods for Enhancing Pluripotent Stem Cell Expansion. Frontiers in Cell and Developmental Biology,8: 70. 2020. [Open Access]
  32. Arora S, Lin S, Cheung C. EKF Yim, YC Toh. Topography elicits distinct phenotypes and functions in human primary and stem cell derived endothelial cells. Biomaterials, 234: 119747. 2020. [Open Access]
  33. Rizwan M, Yao Y, Gorbet M, Tse J, Anderson DEJ, Hinds MT, Yim EKF, One-pot covalent grafting of gelatin on polyvinyl alcohol hydrogel to enhance endothelialization and hemocompatibility for synthetic vascular graft applications. ACS Applied Bio Materials, 3(1): 693-703. 2020. [PMC Free Article]
  34. Koh LB, Zuo K, Praveen Kumar G, Ding X, Leo HL, Cui F, Charles CJ, Yang YY, Yim EKF, Ho P. Optimization of a novel preferential covered stent for atheroembolic carotid stenosis through bench experiments and in vitro platelet activation studies. ACS Biomaterials Science and Engineering, 5(11): 6216-6230. 2019.
  35. Son Y*, Tse JW*^, Zhou Y*, Mao W, Yim EKF, Yoo HS. Biomaterials and controlled release strategy for epithelial wound healing.  Biomaterials Science, 7(11): 4444-4471. 2019. *co-first authors [Open Access]
  36. Jain D, Mattiassi S, Goh EG, Yim EKF. Extracellular matrix and biomimetic engineering microenvironment for neuronal differentiation. Neural Regeneration Research, 15(4):573-585. 2019. [Open Access]
  37. Xia S, Lim YB, Zhang Z, Wang Y, Zhang S, Lim CT, Yim EKF, Kanchanawong P. Nanoscale Architecture of the Cortical Actin Cytoskeleton in Embryonic Stem Cells. Cell Report, 28(5): 1251-1267. 2019. [Open Access]
  38. Anderson DEJ, Truong K, Hagen M, Yim EKF, Hinds M. Biomimetic Modification of Poly(vinyl alcohol): Encouraging Endothelialization and Preventing Thrombosis with Antiplatelet Monotherapy. Acta Biomaterialia, 86: 291-299. 2019. [PMC Free Article]
  39. Arora S, Yim EKF, Toh YC. Environmental specification of pluripotent stem cell derived endothelial cells towards arterial and venous subtypes. Frontiers in Bioengineering and Biotechnology 7: 143. 2019 [Open Access]
  40. Pohan G, Chevallier P, Andersan DEJ, Tse JW, Yao Y, Hagen MW, Mantovani D, Hinds MT, Yim EKF. Luminal Plasma Treatment for Small Diameter Polyvinyl Alcohol Tubular Scaffolds. Frontiers in Bioengineering and Biotechnology, 7. 2019.  [Open Access]
  41. Xia S, Yim EKF, Kanchanawong P. Molecular organization of integrin-based adhesion complexes in mouse embryonic stem cells. ACS Biomaterials Science and Engineering, 5(8): 3828-3842. 2019.
  42. Arora S, Lam JYA, Cheung C, Yim EKF, Toh YC. Determination of critical shear stress for maturation of human pluripotent stem cell-derived endothelial cells towards an arterial subtype. Biotechnology and Bioengineering,116(5): 1164-1175. 2019. [PubMed]
  43. Jurney PL, Anderson DEJ, Pohan G, Yim EKF, Hinds MT. Reactive Ion Plasma Modification of Poly (Vinyl‐Alcohol) Increases Primary Endothelial Cell Affinity and Reduces Thrombogenicity. Macromolecular Bioscience, 18(11): 1800132. 2019. [PMC Free Article]
  44. Yip AK, Nguyen AT, Rizwan M, Wong ST, Chiam KH, Yim EKF. Anisotropic traction stresses and focal adhesion polarization mediates topography-induced cell elongation. Biomaterials, 181:103-112. 2018. [PubMed]
  45. Andersons DEJ, Pohan G, Raman J, Konecny F, Yim EKF, Hinds M. Improving Surgical Methods for Studying Vascular Grafts in Animal Models. Tissue Engineering Part C: Methods, 24(8), 457 -464. 2018. [PMC Free Article]
  46. Tan KKB, Lim WWM, Chai C, Kukumberg M, Lim KL, Goh ELK, Yim EKF. Sequential Application of Discrete Topographical Patterns Enhances Derivation of Functional Mesencephalic Dopaminergic Neurons from Human Induced Pluripotent Stem Cells. Scientific Report, 8: 9567. 2018. [Open Access]
  47. Ankam S, Teo BKK, Pohan G, Ho SWL, Lim CK, Yim EKF. Temporal changes in nucleus morphology, lamin A/C and histone methylation during nanotopography-induced neuronal differentiation of stem cells. Frontier Bioengineering and Biotechnology, 6. 2018. [Open Access]
  48. Kukumberg M, Yao Y, Goh SH, Neo DJH, Yao JY, Yim EKF. Evaluation of the topographical influence on the cellular behavior of human umbilical vein endothelial cells. Advanced Biosystem, 2, 1700217. 2018. [PMC Free Article]
  49. Zeng Y, Wong ST, Teo SK, Leong KW, Chiam K-H, Yim EKF. Human mesenchymal stem cell basal membrane bending on gratings is dependent on both grating width and curvature. Scientific Report, 8: 6444. 2018. [Open Access]
  50. Nguyen A T, Mattiassi S, Loeblein M, Chin E, Ma DL, Coquet P, Viasnoff V, Teo EHT, Goh EL, Yim EKF. Human Rett-derived neuronal progenitor cells in 3D graphene scaffold as an in vitro platform to study the effect of electrical stimulation on neuronal differentiation. Biomedical Materials, 13(3): 034111.2018. [Open Access]
  51. Zeng Y, Wong S T, Teo S K, Teo SK, Leong KW, Keng HC, Yim EKF. Human mesenchymal stem cell basal membrane bending on gratings is dependent on both grating width and curvature. Scientific reports, 8:1-13. 2018. [Open Access]
  52. Ankam S, Teo B K K, Pohan G, Ho SWL, Lim CK, Yim EKF. Temporal changes in nucleus morphology, lamin A/C and histone methylation during nanotopography-induced neuronal differentiation of stem cells[J]. Frontiers in bioengineering and biotechnology, 6:69. 2018. [Open Access]
  53. Cutiongco MFA, Chua BMX, Neo DJH, Rizwan M, Yim EKF. Functional differences between healthy and diabetic endothelial cells on topographical cues. Biomaterials, 153: 70-84. 2017. [PubMed]
  54. Sathe S, Chan XQ, Jin J, Bernitt E, Dobereiner HG, Yim EKF. Correlation and Comparison of Cortical and Hippocampal Neural Progenitor Morphology and Differentiation through the Use of Micro and Nano Topographies. Journal of Functional Biomaterials, 8(3):35. 2017. [Open Access]
  55. Rizwan M, Peh GSL, Ang H-P, Lwin NC, Adnan K, Mehta JS, Tan WS, Yim EKF.  Sequentially-crosslinked bioactive hydrogels as nano-patterned substrates with customizable stiffness and degradation for corneal tissue engineering applications.  Biomaterials, 120: 139-154. 2017. [PubMed]
  56. Kukumberg M, Yao JY, Neo JHD, Yim EKF. Microlens topography combined with vascular endothelial growth factor induces endothelial differentiation of human mesenchymal stem cells into vasculogenic progenitors. Biomaterials, 131:68-85. 2017.  [PubMed]
  57. Kawauchi K, Fujita H, Miyoshi D, Yim EKF, Hirata H.  Cell and molecular mechanics in health and disease.  BioMed Research International.  2017; Article ID 2860241, 2 pages. [Open Access]
  58. Wan ACA, Cutiongco MFA, Tai BCU, Leong MF, Lu HF, Yim EKF.  Fibers by interfacial polyelectrolyte complexation - processes, materials and applications.  Materials Today, 1(1). 2016. [Open Access]
  59. Sonam S, Sathe SR, Yim EKF, Sheetz MP, Lim CT. Cell contractility arising from topography and shear flow determines human mesenchymal stem cell fate. Scientific Reports - UK. 6. 2016. [Free PMC Article]
  60. Rizwan M, Peh GS, Adnan K, Naso SL, Mendez AR, Mehta JS^, Yim EKF^. In-vitro topographical model of Fuchs dystrophy for evaluation of corneal endothelial cell monolayer formation. Advance Healthcare Materials, 5: 2896–2910. 2016. ^co-corresponding authors  [PubMed]
  61. Nguyen AT, Sathe SR, and Yim EKF.  From nano to micro: Topographical scale and its impact on cell adhesion, morphology and contact guidance.  Journal of Physics: Condensed Matter, 28: 183001. 2016. [PubMed]
  62. Monzo P, Chong YK, Guetta-Terrier C, Krishnasamy A, Sathe SR, Yim EKF, Ng WH, Ang BT, Tang C, Ladoux B, Gauthier NC, Sheetz MP. Mechanical confinement triggers glioma linear migration dependent on formin FHOD3. Molecular Biology of the Cell, 27: 1246-1261. 2016. [Free PMC Article]
  63. Lee K, Kim EH, Oh N, Nguyen AT, Bae NH, Lee SJ, Lee KG, Eom C-Y, Yim EK, Park S. Contribution of actin filaments and microtubules to cell elongation and alignment depends on the grating depth of micro gratings. Journal of Nanobiotechnology, 14: 1. 2016. [Free PMC Article]
  64. Cutiongco MFA, Kukumberg M, Peneyra JL, Yeo MS, Yao JY, Rufaihah AJ, Le Visage C, Ho JP, Yim EKF. Submillimeter diameter poly(vinyl alcohol) vascular graft patency in rabbit model. Frontier Bioengineering and Biotechnology, 4: 44. 2016. [Open Access]
  65. Cutiongco MA*, Goh SH*, Aid R, Le Visage C, Low HY, Yim EKF. Planar and tubular patterning of micro- and nano-topographies on poly(vinyl alcohol) hydrogel for improved endothelial cell responses. Biomaterials, 84:184-195. *co-first authors 2016. [PubMed]
  66. Tan KK*, Tann JY*, Sathe SR, Goh SH, Ma DL, Goh EL, Yim EKF. Enhanced differentiation of neural progenitor cells into neurons of the mesencephalic dopaminergic subtype on topographical patterns. Biomaterials, 43: 32-43. 2015. *co-first authors [Journal Website]
  67. Tan KKB*, Giam CSY, Leow MY, Chan CW^, Yim EKF*^. Differential cell adhesion of breast cancer stem cells on biomaterial substrate with nanotopographical cues. Journal of Functional Biomaterials, 6: 241-258. 2015. *co-first authors; ^co-corresponding authors [Open Access]
  68. Muhammad R, Peh GSL, Adnan K, Law JBK, Mehta JS, Yim EKF. Micro- and nano-topography to enhance proliferation and sustain functional markers of donor-derived primary human corneal endothelial cells. Acta Biomaterialia, 19: 138-148. 2015. [PubMed]
  69. Cutiongco MFA, Teo BKK, Yim EKF. Composite scaffolds of interfacial polyelectrolyte fibers for temporally controlled release of biomolecules. Journal of Visualized Experiments, 102: 1-9. 2015. [PubMed]
  70. Cutiongco MFA, Anderson DEJ, Hinds MT, Yim EKF.  In vitro and ex vivo hemocompatibility of off-the-shelf modified poly(vinyl alcohol) vascular grafts.  Acta Biomaterialia, 25:97-108. 2015. [Free PMC Article]
  71. Ankam S*, Lim CK*, Yim EKF. Actomyosin contractility plays a role in MAP2 expression during nanotopography-directed neuronal differentiation of human embryonic stem cells. Biomaterials, 47: 20-28. 2015. *co-first authors  [PubMed]
  72. Cutiongco MFA, Choo RKT, Shen NJX, Chua BMX, Sju E, Choo AWL, Le Visage C, Yim EKF.  Composite scaffold of poly(vinyl alcohol) and interfacial polyelectrolyte complexation fibers for controlled biomolecule delivery.  Frontiers in Bioengineering and Biotechnology, 3. 2015. [Open Access]
  73. Yim EKF, Ankam S, Moe AAK, Chan LYT. Effect of spatial arrangement of substrate topography on neuronal differentiation of stem cells. IFMBE Proceedings, 60-63. 2014. [Journal Website]
  74. Wong ST, Teo SK, Park S, Chiam KH, Yim EKF. Anisotropic rigidity sensing on grating topography directs human mesenchymal stem cell elongation. Biomechanics and Modeling in Mechanobiology, 13(1): 27-39.  2014. [PubMed]
  75. Teo BKK, Wong ST, Lim CK, Kung TYS, Yap CH, Ramgopal Y, Romer LH, Yim EKF. Understanding nanotopography induced stem cell differentiation: A focus on focal adhesion Kinase. IFMBE Proceedings, 36-39. 2014. [Journal Website]
  76. Teo BKK, Tan GDS, Yim EKF. The synergistic effect of nanotopography and sustained dual release of hydrophobic and hydrophilic neurotrophic factors on human mesenchymal stem cell neuronal lineage commitment. Tissue Engineering - Part A, 20(15-16): 2151-2161. 2014. [PubMed]
  77. Muhammad R*, Lim SH*, Goh SH, Law JBK, Saifullah MS, Ho GW, Yim EKF. Sub-100 nm patterning of TiO2 film for the regulation of endothelial and smooth muscle cell functions.  Biomaterials Science, 2(12): 1740-1749. 2014. *co-first authors  [Open Access]
  78. Li K*, Yamamoto M*, Chan SJ, Chiam MY, Qin W, Wong PTH^, Yim EKF^, Tang BZ, Liu B^. Organic nanoparticles with aggregation-induced emission for tracking bone marrow stromal cells in rat ischemic stroke model. Chemical Communications, 50(96): 15136-15139. 2014. *co-first authors; ^ co-corresponding authors  [PubMed]
  79. Koo S, Muhammad R, Peh GS, Mehta JS, Yim EKF. Micro- and nanotopography with extracellular matrix coating modulate human corneal endothelial cell behaviour. Acta Biomaterialia, 10(5): 1975-1984. 2014. [PubMed]
  80. Cutiongco MFA, Tan MH, Ng MYK, Le Visage C, Yim EKF. Composite pullulan-dextran polysaccharide scaffold with interfacial polyelectrolyte complexation fibers: A platform with enhanced cell interaction and spatial distribution. Acta Biomaterialia, 10(10): 4410-4418. 2014. [PubMed]
  81. Chua JS, Chng C-P, Moe AAK, Tann JY, Goh EL, Chiam K-H, and Yim EKF.  Extending neurites sense the depth of the underlying topography during neuronal differentiation and contact guidance.  Biomaterials, 35(27): 7750-7761. 2014. [PubMed]
  82. Teo BKK, Wong ST, Lim CK, Kung TYS, Yap CH, Ramagopal Y, Romer LH, Yim EK. Nanotopography modulates mechanotransduction of stem cells and induces differentiation through focal adhesion kinase. ACS Nano, 7(6): 4785-4798. 2013. [PubMed]
  83. Ino JM, Sju E, Ollivier V, Yim EKF, Letourneur D, Le Visage C. Evaluation of hemocompatibility and endothelialization of hybrid poly(vinyl alcohol) (PVA)/gelatin polymer films. Journal of Biomedical Materials Research - Part B: Applied Biomaterials, 101(8): 1549-1559. 2013. [PubMed]
  84. Chua JS, Liew LX, Yim EKF. Cultivation of human microvascular endothelial cells on topographical substrates to mimic the human corneal endothelium. Journal of Functional Biomaterials, 4(1): 38-58. 2013. [Open Access]
  85. Chan LY, Yim EKF, Choo ABH. Normalized median fluorescence: An alternative flow cytometry analysis method for tracking human embryonic stem cell states during differentiation. Tissue Engineering - Part C: Methods, 19(2): 156-165. 2013. [PubMed]
  86. Chan LY, Birch WR, Yim EKF^, Choo ABH^. Temporal application of topography to increase the rate of neural differentiation from human pluripotent stem cells. Biomaterials, 34(2): 382-392. 2013. ^co-corresponding authors  [PubMed]
  87. Ankam S, Teo BKK, Kukumberg M, Yim EKF. High throughput screening to investigate the interaction of stem cells with their extracellular microenvironment. Organogenesis. 9(3): 128-142. 2013. [Free PMC Article]
  88. Ankam S, Suryana M, Chan LY, Moe AAK, Teo BKK, Law JBK, Sheetz MP, Low HY, Yim EKF. Substrate topography and size determines the fate of human embryonic stem cells to neuronal or glial lineage. Acta Biomaterialia, 9(1): 4535–4545. 2013. [PubMed]
  89. Yim EKF, Sheetz MP.  Force dependent cell signaling in stem cell differentiation. Stem Cell Research and Therapy, 3(41): 38-40. 2012. [Open Access]
  90. Teo BKK, Goh KJ, Ng ZJ, Koo S, Yim EKF. Functional reconstruction of corneal endothelium using nanotopography for tissue-engineering applications. Acta Biomaterialia, 8(8): 2941-2952. 2012. [PubMed]
  91. Moe AAK, Suryana M, Marcy GT, Lim SK, Ankam S, Goh JZW, Jin J, Teo BKK, Law JBK, Low HY, Goh ELK, Sheetz MP, Yim EKF. Microarray with micro- and nano-topographies enables identification of optimal topography to direct differentiation of primary murine neural progenitor cells. Small, 8(19): 3050-3061. 2012. [PubMed]
  92. Teo BKK, Goh KJY, Ng ZJ, Koo S, Yim EKF. Nanotopography enhanced function of corneal endothelial cells for corneal tissue engineering. Acta Biomaterialia, 8(8): 2941-2952. 2012. [PubMed]
  93. Teo BKK*, Goh SH*, Kustandi TS, Loh WW, Low HY, Yim EKF. The effect of micro and nanotopography on endocytosis in drug and gene delivery systems. Biomaterials, 32: 9866-9875. 2011. *co-first authors    
  94. Yow SZ, Lim TH, Lim CT, Yim EKF, Leong KW.  A 3D electroactive polypyrrole-collagen fibrous scaffold for tissue engineering. Polymers, 3: 527-544. 2011.
  95. Koo S*, Ahn SJ*, Zhang H, Wang JC, Yim EKF. Human corneal keratocyte response to micro- and nano-gratings on chitosan and polydimethylsiloxane. Cellular and Molecular Bioengineering, 4: 399-410. 2011. *co-first authors [Journal Website]
  96. Ino J, Sju E, Yim E, Letourneur D, Le Visage C. Incorporation of gelatin into chemically-cross-linked poly-vinyl alcohol (PVA) hydrogels for endothelial cell culture. 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials, 2011.
  97. Yim EKF, Darling EM, Kulangara K, Guilak F, Leong KW. Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells.  Biomaterials, 31: 1299-1306. 2010. [Free PC Article]
  98. Yim EK, Ng ZJ, Teo KK, Ang SJ. Micro- and nano-topography as biomechanical cues for cornea regeneration. IFMBE Proceedings, 1659-1662. 2010. [PubMed]
  99. Teo BKK, Ankam S, Chan LY, Yim EKF. Nanotopography/mechanical induction of stem-cell differentiation. Methods in Cell Biology, 98: 241-294. 2010. [PubMed]
  100. Yow SZ, Quek CH, Yim EKF, Lim CT, Leong KW.  Collagen-based fibrous scaffold for spatial organization of encapsulated and seeded human mesenchymal stem cells. Biomaterials, 30: 1133-1142. 2009. [Free PMC Article]
  101. Yow SZ, Quek CH, Yim EKF, Leong KW, Lim CT.  A biofunctional fibrous scaffold for the encapsulation of human mesenchymal stem cells and its effects on stem cell differentiation. IFMBE Proceedings, 1279-1281. 2009. [PubMed]
  102. Yim EKF, Sefton MV.  Amidine surface modification of poly(acrylonitrile-co-vinyl chloride) reduces platelet adhesion. Journal of Biomedical Materials Research - Part A, 89: 780-790. 2009. [PubMed]
  103. Teo KK, Yim EKF.  Nano-patterned poly-ε-caprolactone with controlled release of retinoic acid and nerve growth factor for neuronal regeneration. IFMBE Proceedings, 1348-1351. 2009.
  104. Yow SZ, Quek CH, Yim EKF, Lim CT, Leong KW. Collagen-based fibrous scaffold for spatial organization of encapsulated and seeded human mesenchymal stem cells biomaterials. Biomaterials, 30: 1133-1142. 2008. [Free PMC Article]
  105. Nori A, Yim EKF, Chen S, Leong KW. Cell-substrate interactions. Principles of Regenerative Medicine, 666-685. 2008. [PubMed]
  106. Yim EKF, Pang SW, Leong KW. Synthetic nanostructures inducing differentiation of human mesenchymal stem cells into neuronal lineage. Experimental Cell Research, 313: 1820-1829. 2007. [Free PMC Article]
  107. Yim EKF, Liao IC, Leong KW. Tissue compatibility of interfacial polyelectrolyte complexation fibrous scaffold: Evaluation of blood compatibility and biocompatibility. Tissue Engineering, 13: 423-433. 2007. [Free PMC Article]
  108. Yim EKF, Wen J, Leong KW. Enhanced extracellular matrix production and differentiation of human embryonic germ cell derivatives in biodegradable poly (ε-caprolactone-co-ethyl ethylene phosphate) scaffold. Acta Biomaterialia, 2: 365-376. 2006. [PubMed]
  109. Yim EKF, Wan ACA, Le Visage C, Liao IC, Leong KW. Proliferation and differentiation of human mesenchymal stem cell encapsulated in polyelectrolyte complexation fibrous scaffold. Biomaterials, 27: 6111-6122. 2006. [PubMed]
  110. Yim EKF, Reano RM, Pang SW, Yee AF, Chen CS, Leong KW. Nanopattern-induced changes in morphology and motility of smooth muscle cells. Biomaterials, 26: 5405-5413. 2005. [Free PMC Article]
  111. Yim EKF, Leong KW.  Significance of synthetic nanostructures in dictating cellular response. Nanomedicine: Nanotechnology, Biology, and Medicine,1: 10-21. 2005. [PubMed]
  112. Yim EKF, Leong KW. Proliferation and differentiation of human embryonic germ cell derivatives in bioactive polymeric fibrous scaffold. Journal of Biomaterials Science: Polymer Edition, 16: 1193-1217. 2005. [PubMed]
  113. Liao IC, Wan ACA, Yim EKF, Leong KW. Controlled release from fibers of polyelectrolyte complexes.  Journal of Controlled Release, 104: 347-358. 2005. [PubMed]
  114. Hu W, Yim EKF, Reano RM, Leong KW, Pang SW. Effects of nanoimprinted patterns in tissue-culture polystyrene on cell behaviour. Journal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures, 23: 2984-2989. 2005. [Free PMC Article]
  115. Chew SY, Wen J, Yim EKF, Leong KW. Sustained release of proteins from electrospun biodegradable fibres. Biomacromolecules, 6: 2017-2024. 2005. [PubMed] 
  116. Yim EKF, Leong KW. Significance of synthetic nanostructures in dictating cellular response.  Nanomedicine: Nanotechnology, Biology, and Medicine, 1: 10-21. 2005. [PubMed]
  117. Yim EKF, Wan A, Liao IC, Le Visage C, Leong KW. Osteogenic and chondrogenic differentiation of human mesenchymal stem cells incorporated into polyelectrolyte fibrous scaffold. Transactions - 7th World Biomaterials Congress, 165. 2004. [Free PMC Article]
  118. Wan ACA*, Yim EKF*, Liao IC, Le Visage C, and Leong KW.  Encapsulation of biologics in self-assembled fibers as biostructural units for tissue engineering.  Journal of Biomedical Materials Research - Part A, 71: 586-595. 2004. *co-first authors  [PubMed]
  119. Wan ACA, Yim EKF, Liao IC, Chai C, Leong KW. The assembly of "biostructural units" as a new strategy for tissue engineering. Transactions - 7th World Biomaterials Congress, 1543. 2004.
  120. Wan ACA, Liao IC, Yim EKF, Leong KW. Mechanism of fiber formation by interfacial polyelectrolyte complexation. Macromolecules, 37(18): 7019-7025. 2004. [PubMed]
  121. Leong KW, Liao IC, Yim EKF, Lim S, Wan A, Wen J, Chew SY, Chua KN, Ramakrishna, S, Mao HQ.  Controlled release systems designed for regenerative medicine.  Transactions - 7th World Biomaterials Congress, 189. 2004.
  122. Rizwan M, Chan S, Comeau P, Willett T, Yim EKF. Effect of sterilization treatment on mechanical properties, biodegradation, bioactivity and printability of GelMA hydrogels. Biomedical Materials. In press, 15(6):065017. 2020. [PubMed]
  123. Jeong Y, Yao Y, Yim EKF. Current understanding of intimal hyperplasia and effect of compliance in synthetic small diameter vascular grafts. Biomaterials Science. In press, 8(16):4383-4395. 2020. [PubMed]
  124. Zuo K, Koh LB, Charles CJ, Yim EK, Lim J, Li RR, Leo HL, Cui F, Ho P. Measurement of the Luminal Diameter of Peripheral Arterial Vasculature in Yorkshire× Landrace Swine by Using Ultrasonography and Angiography. Journal of the American Association for Laboratory Animal Science: JAALAS. In press, 50(5):628–634. 2020. [Free PMC Article]
  125. Yao Y, Zaw AM, Anderson D, Hinds MT, Yim EKF. Fucoidan functionalization on poly(vinyl alcohol) hydrogels for improved endothelialization and hemocompatibility. Biomaterials. In press, 249:120011. 2020. [PubMed]
  126. Chan S, Rizwan M, Yim EKF. Emerging Methods for Enhancing Pluripotent Stem Cell Expansion. Frontiers in Cell and Developmental Biology, 8: 70. 2020. [Free PMC Article]
  127. Arora S, Lin S, Cheung C, Yim EKF^, Toh YC^. Topography elicits distinct phenotypes and functions in human primary and stem cell derived endothelial cells. Biomaterials, 234: 119747. 2020. ^co-corresponding authors [PubMed]
  128. Rizwan M, Yao Y, Gorbet M, Tse J, Anderson DEJ.; Hinds MT, Yim EKF, One-pot covalent grafting of gelatin on polyvinyl alcohol hydrogel to enhance endothelialization and hemocompatibility for synthetic vascular graft applications. ACS Applied Bio Materials, 3(1): 693-703. 2020. [PubMed]
  129. Arora S, Lam AJY, Cheung C, Yim EKF, Toh YC. Determination of critical shear stress for maturation of human pluripotent stem cell‐derived endothelial cells towards an arterial subtype. Biotechnology and bioengineering, 116(5): 1164-1175. 2019. [PubMed]
  130. Koh LB, Zuo K, Kumar GP, Ding X, Leo HL, Cui F, Charles CJ, Yang YY, Yim EKF, Ho P. Optimization of a novel preferential covered stent for atheroembolic carotid stenosis through bench experiments and in vitro platelet activation studies. ACS Biomaterials Science and Engineering, 5(11): 6216-6230. 2019. [PubMed]
  131. Son Y, Tse JW, Zhou Y, Mao W, Yim EKF, Yoo HS. Biomaterials and controlled release strategy for epithelial wound healing. Biomaterials Science, 7(11): 4444-4471. 2019. [PubMed]
  132. Jain D, Mattiassi S, Goh EG, Yim EKF. Extracellular matrix and biomimetic engineering microenvironment for neuronal differentiation. Neural Regeneration Research, 15(4): 573-585. 2019. [Open Access]
  133. Xia S, Lim YB, Zhang Z, Wang Y, Zhang S, Lim CT, Yim EKF, Kanchanawong P. Nanoscale Architecture of the Cortical Actin Cytoskeleton in Embryonic Stem Cells. Cell Report, 28(5): 1251-1267. E7.2019. [Open Access]
  134. Anderson DEJ, Truong K, Hagen M, Yim EKF, Hinds M. Biomimetic Modification of Poly(vinyl alcohol): Encouraging Endothelialization and Preventing Thrombosis with Antiplatelet Monotherapy. Acta Biomaterialia, 86: 291-299. 2019 [PubMed]
  135. Arora S, Yim EKF, Toh YC. Environmental specification of pluripotent stem cell derived endothelial cells towards arterial and venous subtypes. Frontiers in Bioengineering and Biotechnology, 7:143. 2019. [Open Access]
  136. Pohan G, Chevallier P, Andersan DEJ, Tse JW, Yao Y, Hagen MW, Mantovani D, Hinds MT, Yim EKF. Luminal Plasma Treatment for Small Diameter Polyvinyl Alcohol Tubular Scaffolds. Frontiers in Bioengineering and Biotechnology, 7. 2019. [Open Access]
  137. Xia S, Yim EKF, Kanchanawong P. Molecular organization of integrin-based adhesion complexes in mouse embryonic stem cells. ACS Biomaterials Science and Engineering, 5(8): 3828-3842. 2019. [Open Access]
  138. Arora S, Lam JYA, Cheung C, Yim EKF, Toh YC. Determination of critical shear stress for maturation of human pluripotent stem cell-derived endothelial cells towards an arterial subtype. Biotechnology and Bioengineering, 116(5): 1164-1175. 2019. [PubMed]
  139. Xia S, Yim EKF, Kanchanawong P. Molecular organization of integrin-based adhesion complexes in mouse Embryonic Stem Cells. BioRxiv, 416503, 2018. [Open Access]
  140. Jurney PL, Anderson DEJ, Pohan G, Yim EKF, Hinds MT. Reactive Ion Plasma Modification of Poly (Vinyl‐Alcohol) Increases Primary Endothelial Cell Affinity and Reduces Thrombogenicity. Macromolecular Bioscience, 18(11): 1800132. 2019. [PubMed]
  141. Yip AK, Nguyen AT, Rizwan M, Wong ST, Chiam KH, Yim EKF. Anisotropic traction stresses and focal adhesion polarization mediates topography-induced cell elongation. Biomaterials, 181:103-112. 2018. [Open Access]
  142. Andersons DEJ, Pohan G, Raman J, Konecny F, Yim EKF, Hinds M. Improving Surgical Methods for Studying Vascular Grafts in Animal Models. Tissue Engineering Part C: Methods, 24(8): 457-464. 2018. [PubMed]
  143. Tan KKB, Lim WWM, Chai C, Kukumberg M, Lim KL, Goh ELK, Yim EKF. Sequential Application of Discrete Topographical Patterns Enhances Derivation of Functional Mesencephalic Dopaminergic Neurons from Human Induced Pluripotent Stem Cells. Scientific Report, 8: 9567. 2019. [Open Access]
  144. Ankam S, Teo BKK, Pohan G, Ho SWL, Lim CK, Yim EKF. Temporal changes in nucleus morphology, lamin A/C and histone methylation during nanotopography-induced neuronal differentiation of stem cells. Frontier Bioengineering and Biotechnology, 6(69). 2018.  [Open Access]
  145. Kukumberg M, Yao Y, Goh SH, Neo DJH, Yao JY, Yim EKF. Evaluation of the topographical influence on the cellular behavior of human umbilical vein endothelial cells. Advanced Biosystem. In Press, 6(6). 2018. [Open Access]
  146. Zeng Y, Wong ST, Teo SK, Leong KW, Chiam K-H, Yim EKF. Human mesenchymal stem cell basal membrane bending on gratings is dependent on both grating width and curvature. Scientific Report, 8: 6444. 2018. [Open Access]
  147. Nguyen AT, Mattiassi S, Loeblein M, Chin E, Ma DL, Coquet P, Viasnoff V, Teo E, Goh EL, Yim EKF. Human Rett-derived neuronal progenitor cells in 3D graphene scaffold as an in vitro platform to study the effect of electrical stimulation on neuronal differentiation. Biomedical Materials, 13(3): 034111. 2018. [Open Access]
  148. Cutiongco MFA, Chua BMX, Neo DJH, Rizwan M, Yim EKF. Functional differences between healthy and diabetic endothelial cells on topographical cues. Biomaterials, 153: 70-84. 2018. [PubMed]
  149. Sathe S, Chan XQ, Jin J, Bernitt E, Döbereiner H-G, Yim EKF. Correlation and Comparison of Cortical and Hippocampal Neural Progenitor Morphology and Differentiation through the Use of Micro-and Nano-Topographies. Journal of Functional Biomaterials, 8(3): 35. 2017. [Open Access]
  150. Kukumberg M, Yao JY, Neo JHD, Yim EKF. Microlens topography combined with vascular endothelial growth factor induces endothelial differentiation of human mesenchymal stem cells into vasculogenic progenitors. Biomaterials, 131:68-85. 2017. [Open Access]
  151. Kawauchi K, Fujita H, Miyoshi D, Yim EKF, Hirata H. Cell and Molecular Mechanics in Health and Disease, BioMed Research International 2017; Article ID 2860241, 2 pages. 2017. [Open Access]
  152. Rizwan M, Peh GSL, Ang H-P, Lwin NC, Adnan K, Mehta JS, Tan WS, Yim EKF. Sequentially-crosslinked bioactive hydrogels as nano-patterned substrates with customizable stiffness and degradation for corneal tissue engineering applications. Biomaterials, 120: 139-154. 2017. [PubMed]
  153. Rizwan M, Peh GS, Adnan K, Naso SL, Mendez AR, Mehta JS^, Yim EKF^. In-vitro topographical model of Fuchs dystrophy for evaluation of corneal endothelial cell monolayer formation. Advance Healthcare Materials. 5: 2896–2910. 2016. ^co-corresponding authors [PubMed]
  154. Cutiongco MFA, Kukumberg M, Peneyra JL, Yeo MS, Yao JY, Rufaihah AJ, Le Visage C, Ho JP, Yim EKF. Submillimeter Diameter Poly(Vinyl Alcohol) Vascular Graft Patency in Rabbit Model. Frontier Bioengineering and Biotechnology, 4: 44. 2016. [Free PMC Article]
  155. Lee K, Kim EH, Oh N, Nguyen AT, Bae NH, Lee SJ, Lee KG, Eom C-Y, Yim EKF, Park S. Contribution of actin filaments and microtubules to cell elongation and alignment depends on the grating depth of microgratings. Journal of Nanobiotechnology, 14 (1): 1, 2016. Free PMC Article]
  156. Sonam S, Sathe SR, Yim EKF, Sheetz MP, Lim CT. Cell contractility arising from topography and shear flow determines human mesenchymal stem cell fate. Scientific Reports, 6: 20415. 2016. [Open Access]
  157. Wan ACA, Cutiongco MFA, Tai BCU, Leong MF, Lu HF, Yim EKK. Fibers by Interfacial Polyelectrolyte Complexation- Processes, Materials and Applications. Materials Today, 19(8): 437-450. 2016. [Open Access]
  158. Nguyen AT, Sathe SR, Yim EKF. From nano to micro: topographical scale and its impact on cell adhesion, morphology and contact guidance. Journal of Physics: Condensed Matter, 28(18): 183001. 2016. [PubMed]
  159. Monzo P, Chong YK, Guetta-Terrier C, Krishnasamy A, Sathe SF, Yim EKF, Ng WH, Ang BT, Tang C, Ladoux B, Gauthier NC, Sheetz MP. Mechanical confinement triggers glioma linear migration dependent on formin FHOD3. Molecular Biology of the Cell, 27(8): 1246–1261. 2016. [Free PMC Article]
  160. Cutiongco MA*, Goh SH*, Aid R, Le Visage C, Low HY, Yim EKF. Planar and Tubular Patterning of Micro and Nano-topographies on Poly(vinyl alcohol) Hydrogel for Improved Endothelial Cell Responses. Biomaterials, 84:184-195. 2016. *co-first authors [PubMed]
  161. Cutiongco MA, Anderson DEJ, Hinds MT, Yim EKF. In vitro and ex vivo hemocompatibility of off-the-shelf modified poly(vinyl alcohol) vascular grafts. Acta Biomaterialia, 25: 97-108. 2015. [Free PMC Article]
  162. Tan KKB*, Giam CSY, Leow MY, Chan CW^, Yim EKF*^. Differential Cell Adhesion of Breast Cancer Stem Cells on Biomaterial Substrate with Nanotopographical Cues. Journal of Functional Biomaterials, 6(2): 241-58. 2015. *co-first authors; ^co-corresponding authors [Open Access]
  163. Muhammad R, Peh GSL, Adnan K, Law JBK, Mehta JS, Yim EKF. Micro- and nano-topography to enhance proliferation and sustain functional markers of donor-derived primary human corneal endothelial cells. Acta Biomaterialia, 19: 138-48. 2015. [PubMed]
  164. Cutiongco MA, Teo KKB, Yim EKF. Composite scaffolds of interfacial polyelectrolyte fibers for temporally controlled release of biomolecules. Journal of Visualized Experiments, 102. 2015. [Free PMC Article]
  165. Ankam S*, Lim CK*, Yim EKF. Actomyosin contractility plays a role in expression of MAP2 during neuronal differentiation of human embryonic stem cells. Biomaterials, 47: 20-28. 2015. *co-first authors [PubMed]
  166. Cutiongco MFA, Choo RKT, Shen NJX, Chua BMX, Sju E, Choo AWL, Le Visage C, Yim EKF. Composite scaffold of poly(vinyl alcohol) and interfacial polyelectrolyte complexation fibers for controlled biomolecule delivery. Frontiers in Bioengineering and Biotechnology, 3:3. 2015. [Open Access]
  167. Tan KK*, Tann JY*, Sathe SR, Goh SH, Ma DL, Goh EL, Yim EKF. Enhanced Differentiation of Neural Progenitor Cells into Neurons of the Mesencephalic Dopaminergic Subtype on Topographical Patterns. Biomaterials, 43: 32-43. 2015. *co-first authors [PubMed]

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