Publications

  1. Rizwan M, Peh GSL, Ang H-P, Lwin NC, Adnan K, Mehta JS, Tan WS, and Yim EKF.  Sequentially-crosslinked bioactive hydrogels as nano-patterned substrates with customizable stiffness and degradation for corneal tissue engineering applications.  Biomaterials.  2017; 120: 139-154.  [PubMed]
  2. Kukumberg M, Yao JY, Neo JHD, and Yim EKF.  Microlens topography combined with vascular endothelial growth factor induces endothelial differentiation of human mesenchymal stem cells into vasculogenic progenitors.  Biomaterials.  2017.  [PubMed]
  3. Kawauchi K, Fujita H, Miyoshi D, Yim EKF, and Hirata H.  Cell and molecular mechanics in health and disease.  BioMed Research International.  2017; Article ID 2860241, 2 pages.  [Open Access]
  4. Wan ACA, Cutiongco MFA, Tai BCU, Leong MF, Lu HF, and Yim EKF.  Fibers by interfacial polyelectrolyte complexation - processes, materials and applications.  Materials Today.  2016.  [Journal Website]
  5. Sonam S, Sathe SR, Yim EKF, Sheetz MP, and Lim CT.  Cell contractility arising from topography and shear flow determines human mesenchymal stem cell fate.  Scientific Reports - UK.  2016; 6.  [Free PMC Article]
  6. Rizwan M, Peh GS, Adnan K, Naso SL, Mendez AR, Mehta JS^, and Yim EKF^.  In-vitro topographical model of Fuchs dystrophy for evaluation of corneal endothelial cell monolayer formation.  Advance Healthcare Materials.  2016; 5: 2896–2910. ^co-corresponding authors  [PubMed]  
  7. Nguyen AT, Sathe SR, and Yim EKF.  From nano to micro: Topographical scale and its impact on cell adhesion, morphology and contact guidance.  Journal of Physics: Condensed Matter.  2016; 28: 183001.  [PubMed]    
  8. Monzo P, Chong YK, Guetta-Terrier C, Krishnasamy A, Sathe SR, Yim EKF, Ng WH, Ang BT, Tang C, Ladoux B, Gauthier NC, and Sheetz MP.  Mechanical confinement triggers glioma linear migration dependent on formin FHOD3.  Molecular Biology of the Cell.  2016; 27: 1246-1261.  [Free PMC Article]  
  9. Lee K, Kim EH, Oh N, Nguyen AT, Bae NH, Lee SJ, Lee KG, Eom C-Y, Yim EK, and Park S.  Contribution of actin filaments and microtubules to cell elongation and alignment depends on the grating depth of micro gratings.  Journal of Nanobiotechnology.  2016; 14: 1.  [Free PMC Article]
  10. Cutiongco MFA, Kukumberg M, Peneyra JL, Yeo MS, Yao JY, Rufaihah AJ, Le Visage C, Ho JP, and Yim EKF.  Submillimeter diameter poly(vinyl alcohol) vascular graft patency in rabbit model.  Frontier Bioengineering and Biotechnology.  2016; 4: 44. Doi: 10.3389/fbioe.2016.00044. [Open Access]
  11. Cutiongco MA*, Goh SH*, Aid R, Le Visage C, Low HY, and Yim EKF.  Planar and tubular patterning of micro- and nano-topographies on poly(vinyl alcohol) hydrogel for improved endothelial cell responses.  Biomaterials.  2016; 84:184-195. *co-first authors  [PubMed]    
  12. Tan KK*, Tann JY*, Sathe SR, Goh SH, Ma DL, Goh EL, and Yim EKF.  Enhanced differentiation of neural progenitor cells into neurons of the mesencephalic dopaminergic subtype on topographical patterns.  Biomaterials. 2015; 43: 32-43. *co-first authors  [Journal Website]
  13. Tan KKB*, Giam CSY, Leow MY, Chan CW^, and Yim EKF*^.  Differential cell adhesion of breast cancer stem cells on biomaterial substrate with nanotopographical cues.  Journal of Functional Biomaterials.  2015; 6: 241-258. *co-first authors; ^co-corresponding authors  [Open Access]
  14. Muhammad R, Peh GSL, Adnan K, Law JBK, Mehta JS, and Yim EKF.  Micro- and nano-topography to enhance proliferation and sustain functional markers of donor-derived primary human corneal endothelial cells.  Acta Biomaterialia.  2015; 19: 138-148.  [PubMed]
  15. Cutiongco MFA, Teo BKK, and Yim EKF.  Composite scaffolds of interfacial polyelectrolyte fibers for temporally controlled release of biomolecules.  Journal of Visualized Experiments.  2015; 102: 1-9.  [PubMed]
  16. Cutiongco MFA, Anderson DEJ, Hinds MT, and Yim EKF.  In vitro and ex vivo hemocompatibility of off-the-shelf modified poly(vinyl alcohol) vascular grafts.  Acta Biomaterialia.  2015; 25:97-108.  [Free PMC Article]
  17. Ankam S*, Lim CK*, and Yim EKF.  Actomyosin contractility plays a role in MAP2 expression during nanotopography-directed neuronal differentiation of human embryonic stem cells.  Biomaterials.  2015; 47: 20-28*co-first authors  [PubMed]
  18. Cutiongco MFA, Choo RKT, Shen NJX, Chua BMX, Sju E, Choo AWL, Le Visage C, and Yim EKF.  Composite scaffold of poly(vinyl alcohol) and interfacial polyelectrolyte complexation fibers for controlled biomolecule delivery.  Frontiers in Bioengineering and Biotechnology.  2015. doI: 10.3389/fbioe.2015.00003. [Open Access]
  19. Yim EKF, Ankam S, Moe AAK, and Chan LYT.  Effect of spatial arrangement of substrate topography on neuronal differentiation of stem cells.  IFMBE Proceedings.  2014; 60-63.  [Journal Website]
  20. Wong ST, Teo SK, Park S, Chiam KH, and Yim EKF.  Anisotropic rigidity sensing on grating topography directs human mesenchymal stem cell elongation.  Biomechanics and Modeling in Mechanobiology.  2014; 13: 27-39.  [PubMed]
  21. Teo BKK, Wong ST, Lim CK, Kung TYS, Yap CH, Ramgopal Y, Romer LH, and Yim EKF.  Understanding nanotopography induced stem cell differentiation: A focus on focal adhesion Kinase.  IFMBE Proceedings.  2014; 36-39.  [Journal Website]
  22. Teo BKK, Tan GDS, and Yim EKF.  The synergistic effect of nanotopography and sustained dual release of hydrophobic and hydrophilic neurotrophic factors on human mesenchymal stem cell neuronal lineage commitment.  Tissue Engineering - Part A.  2014; 20: 2151-2161.  [PubMed]
  23. Muhammad R*, Lim SH*, Goh SH, Law JBK, Saifullah MS, Ho GW, and Yim EKF.  Sub-100 nm patterning of TiO2 film for the regulation of endothelial and smooth muscle cell functions.  Biomaterials Science.  2014; 2: 1740-1749. *co-first authors  [Journal Website]
  24. Li K*, Yamamoto M*, Chan SJ, Chiam MY, Qin W, Wong PTH^, Yim EKF^, Tang BZ, and Liu B^.  Organic nanoparticles with aggregation-induced emission for tracking bone marrow stromal cells in rat ischemic stroke model.  Chemical Communications.  2014; 50: 15136-15139. *co-first authors; ^ co-corresponding authors  [PubMed]
  25. Koo S, Muhammad R, Peh GS, Mehta JS, and Yim EKF.  Micro- and nanotopography with extracellular matrix coating modulate human corneal endothelial cell behaviour.  Acta Biomaterialia.  201410: 1975-1984.  [PubMed]
  26. Cutiongco MFA, Tan MH, Ng MYK, Le Visage C, and Yim EKF.  Composite pullulan-dextran polysaccharide scaffold with interfacial polyelectrolyte complexation fibers: A platform with enhanced cell interaction and spatial distribution.  Acta Biomaterialia.  2014; 10: 4410-4418.  [PubMed]    
  27. Chua JS, Chng C-P, Moe AAK, Tann JY, Goh EL, Chiam K-H, and Yim EKF.  Extending neurites sense the depth of the underlying topography during neuronal differentiation and contact guidance.  Biomaterials.  2014; 35: 7750-7761.  [PubMed]
  28. Teo BKK, Wong ST, Lim CK, Kung TYS, Yap CH, Ramagopal Y, Romer LH, and Yim EK.  Nanotopography modulates mechanotransduction of stem cells and induces differentiation through focal adhesion kinase.  ACS Nano.  2013; 7: 4785-4798.  [PubMed]
  29. Ino JM, Sju E, Ollivier V, Yim EKF, Letourneur D, and Le Visage C.  Evaluation of hemocompatibility and endothelialization of hybrid poly(vinyl alcohol) (PVA)/gelatin polymer films.  Journal of Biomedical Materials Research - Part B: Applied Biomaterials.  2013; 101: 1549-1559.  [PubMed]
  30. Chua JS, Liew LX, and Yim EKF.  Cultivation of human microvascular endothelial cells on topographical substrates to mimic the human corneal endothelium.  Journal of Functional Biomaterials.  2013; 4: 38-58.  [Open Access]
  31. Chan LY, Yim EKF, and Choo ABH.  Normalized median fluorescence: An alternative flow cytometry analysis method for tracking human embryonic stem cell states during differentiation.  Tissue Engineering - Part C: Methods.  2013; 19: 156-165.  [PubMed]
  32. Chan LY, Birch WR, Yim EKF^, and Choo ABH^.  Temporal application of topography to increase the rate of neural differentiation from human pluripotent stem cells.  Biomaterials.  2013; 34: 382-392. ^co-corresponding authors  [PubMed]  
  33. Ankam S, Teo BKK, Kukumberg M, and Yim EKF.  High throughput screening to investigate the interaction of stem cells with their extracellular microenvironment.  Organogenesis.  2013; 9: 194-208.  [Free PMC Article]
  34. Ankam S, Teo BKK, Kukumberg M, and Yim EKF.  High throughput screening to investigate the interaction of stem cells with their extracellular microenvironment.  Organogenesis. 2013; 9: 128-142.  [Free PMC Article]
  35. Ankam S, Suryana M, Chan LY, Moe AAK, Teo BKK, Law JBK, Sheetz MP, Low HY, and Yim EKF.  Substrate topography and size determines the fate of human embryonic stem cells to neuronal or glial lineage.  Acta Biomaterialia.  20139: 4535–4545.  [PubMed] 
  36. Yim EKF and Sheetz MP.  Force dependent cell signalling in stem cell differentiation.  Stem Cell Research and Therapy.  20123: 38-40.  [Open Access]
  37. Teo BKK, Goh KJ, Ng ZJ, Koo S, and Yim EKF.  Functional reconstruction of corneal endothelium using nanotopography for tissue-engineering applications.  Acta Biomaterialia.  2012; 8: 2941-2952.  [PubMed]
  38. Moe AAK, Suryana M, Marcy GT, Lim SK, Ankam S, Goh JZW, Jin J, Teo BKK, Law JBK, Low HY, Goh ELK, Sheetz MP and Yim EKF.  Microarray with micro- and nano-topographies enables identification of optimal topography to direct differentiation of primary murine neural progenitor cells.  Small.  2012; 8: 3050-3061.  [PubMed]
  39. Teo BKK, Goh KJY, Ng ZJ, Koo S and Yim EKF.  Nanotopography enhanced function of corneal endothelial cells for corneal tissue engineering.  Acta Biomaterialia.  2012; 8: 2941-2952.  [PubMed]  
  40. Teo BKK*, Goh SH*, Kustandi TS, Loh WW, Low HY, Yim EKF.  The effect of micro and nanotopography on endocytosis in drug and gene delivery systems.  Biomaterials.  2011; 32: 9866-9875. *co-first authors    
  41. Yow SZ, Lim TH, Lim CT, Yim EKF, and Leong KW.  A 3D electroactive polypyrrole-collagen fibrous scaffold for tissue engineering.  Polymers.  2011; 3: 527-544.
  42. Koo S*, Ahn SJ*, Zhang H, Wang JC and Yim EKF.  Human corneal keratocyte response to micro- and nano-gratings on chitosan and polydimethylsiloxane.  Cellular and Molecular Bioengineering.  2011; 4: 399-410. *co-first authors [Journal Website]
  43. Ino J, Sju E, Yim E, Letourneur D, and Le Visage C.  Incorporation of gelatin into chemically-cross-linked poly-vinyl alcohol (PVA) hydrogels for endothelial cell culture.  24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials.  2011.
  44. Yim EKF, Darling EM, Kulangara K, Guilak F, and Leong KW.  Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells.  Biomaterials.  2010; 31: 1299-1306.  [Free PC Article]
  45. Yim EK, Ng ZJ, Teo KK, and Ang SJ.  Micro- and nano-topography as biomechanical cues for cornea regeneration.  IFMBE Proceedings.  2010; 1659-1662.  [PubMed]
  46. Teo BKK, Ankam S, Chan LY and Yim EKF.  Nanotopography/mechanical induction of stem-cell differentiation.  Methods in Cell Biology.  2010; 98: 241-294.  [PubMed]  
  47. Yow SZ, Quek CH, Yim EKF, Lim CT, and Leong KW.  Collagen-based fibrous scaffold for spatial organization of encapsulated and seeded human mesenchymal stem cells.  Biomaterials.  2009; 30: 1133-1142.  [Free PMC Article]
  48. Yow SZ, Quek CH, Yim EKF, Leong KW, and Lim CT.  A biofunctional fibrous scaffold for the encapsulation of human mesenchymal stem cells and its effects on stem cell differentiation.  IFMBE Proceedings.  2009; 1279-1281.  [Journal Website]
  49. Yim EKF and Sefton MV.  Amidine surface modification of poly(acrylonitrile-co-vinyl chloride) reduces platelet adhesion.  Journal of Biomedical Materials Research - Part A.  2009; 89: 780-790.  [PubMed]
  50. Teo KK and Yim EKF.  Nano-patterned poly-ε-caprolactone with controlled release of retinoic acid and nerve growth factor for neuronal regeneration.  IFMBE Proceedings.  2009; 1348-1351.  [Journal Website]
  51. Yow SZ, Quek CH, Yim EKF, Lim CT, and Leong KW.  Collagen-based fibrous scaffold for spatial organization of encapsulated and seeded human mesenchymal stem cells biomaterials.  Biomaterials.  2008; 30: 1133-1142.  [Free PMC Article]
  52. Nori A, Yim EKF, Chen S, and Leong KW.  Cell-substrate interactions.  Principles of Regenerative Medicine.  2008; 666-685.  [PubMed]
  53. Yim EKF, Pang SW and Leong KW.  Synthetic nanostructures inducing differentiation of human mesenchymal stem cells into neuronal lineage.  Experimental Cell Research.  2007313: 1820-1829.  [Free PMC Article]
  54. Yim EKF, Liao IC, and Leong KW.  Tissue compatibility of interfacial polyelectrolyte complexation fibrous scaffold: Evaluation of blood compatibility and biocompatibility.  Tissue Engineering.  2007; 13: 423-433.  [Free PMC Article]
  55. Yim EKF, Wen J, and Leong KW.  Enhanced extracellular matrix production and differentiation of human embryonic germ cell derivatives in biodegradable poly (ε-caprolactone-co-ethyl ethylene phosphate) scaffold.  Acta Biomaterialia.  2006; 2: 365-376.  [PubMed]
  56. Yim EKF, Wan ACA, Le Visage C, Liao IC, and Leong KW.  Proliferation and differentiation of human mesenchymal stem cell encapsulated in polyelectrolyte complexation fibrous scaffold.  Biomaterials.  2006; 27: 6111-6122.  [PubMed]
  57. Yim EKF, Reano RM, Pang SW, Yee AF, Chen CS, and Leong KW.  Nanopattern-induced changes in morphology and motility of smooth muscle cells.  Biomaterials.  2005; 26: 5405-5413.  [Free PMC Article]
  58. Yim EKF and Leong KW.  Significance of synthetic nanostructures in dictating cellular response.  Nanomedicine: Nanotechnology, Biology, and Medicine.  2005; 1: 10-21.  [PubMed]
  59. Yim EKF and Leong KW.  Proliferation and differentiation of human embryonic germ cell derivatives in bioactive polymeric fibrous scaffold.  Journal of Biomaterials Science: Polymer Edition.  2005; 16: 1193-1217.  [PubMed]
  60. Liao IC, Wan ACA, Yim EKF, and Leong KW.  Controlled release from fibers of polyelectrolyte complexes.  Journal of Controlled Release.  2005; 104: 347-358.  [PubMed]
  61. Hu W, Yim EKF, Reano RM, Leong KW, and Pang SW.  Effects of nanoimprinted patterns in tissue-culture polystyrene on cell behaviour.  Journal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures.  2005; 23: 2984-2989.  [Free PMC Article]
  62. Chew SY, Wen J, Yim EKF, and Leong KW.  Sustained release of proteins from electrospun biodegradable fibres.  Biomacromolecules.  2005; 6: 2017-2024.  [PubMed]  
  63. Yim EKF and Leong KW.  Significance of synthetic nanostructures in dictating cellular response.  Nanomedicine: Nanotechnology, Biology, and Medicine.  2005; 1: 10-21.  [PubMed]
  64. Yim EKF, Wan A, Liao IC, Le Visage C, and Leong KW.  Osteogenic and chondrogenic differentiation of human mesenchymal stem cells incorporated into polyelectrolyte fibrous scaffold.  Transactions - 7th World Biomaterials Congress.  2004: 165.  [Free PMC Article]
  65. Wan ACA*, Yim EKF*, Liao IC, Le Visage C, and Leong KW.  Encapsulation of biologics in self-assembled fibers as biostructural units for tissue engineering.  Journal of Biomedical Materials Research - Part A.  2004; 71: 586-595. *co-first authors  [PubMed]
  66. Wan ACA, Yim EKF, Liao IC, Chai C, and Leong KW.  The assembly of "biostructural units" as a new strategy for tissue engineering.  Transactions - 7th World Biomaterials Congress.  2004; 1543.  [Journal Website]
  67. Wan ACA, Liao IC, Yim EKF, and Leong KW.  Mechanism of fiber formation by interfacial polyelectrolyte complexation.  Macromolecules.  200437: 7019-7025.  [Journal Website]
  68. Leong KW, Liao IC, Yim E, Lim S, Wan A, Wen J, Chew SY, Chua KN, Ramakrishna, S, and Mao HQ.  Controlled release systems designed for regenerative medicine.  Transactions - 7th World Biomaterials Congress.  2004; 189.